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Related Concept Videos

Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...

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Related Experiment Video

Updated: May 13, 2026

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
08:53

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma

Published on: June 10, 2017

Non-Hodgkin's lymphomas, version 1.2013.

Andrew D Zelenetz1, William G Wierda, Jeremy S Abramson

  • 1Memorial Sloan-Kettering Cancer Center, USA.

Journal of the National Comprehensive Cancer Network : JNCCN
|March 15, 2013
PubMed
Summary
This summary is machine-generated.

NCCN Guidelines for Non-Hodgkin's Lymphomas (NHL) have been updated. New recommendations cover chronic lymphocytic leukemia treatments and managing hepatitis virus infections in high-risk NHL patients undergoing therapy.

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Last Updated: May 13, 2026

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
08:53

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Published on: June 10, 2017

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07:17

Wild-type Blocking PCR Combined with Sanger Sequencing for Detection of Low-frequency Somatic Mutation

Published on: August 23, 2024

Area of Science:

  • Oncology
  • Hematology
  • Clinical Guidelines

Background:

  • Non-Hodgkin's Lymphomas (NHL) encompass a diverse group of lymphoid malignancies.
  • Treatment decisions for NHL require consideration of specific subtypes and patient risk factors.
  • Managing complications like viral reactivation is crucial during antitumor therapy.

Purpose of the Study:

  • To summarize key updates to the NCCN Guidelines for NHL.
  • To provide clinical evidence supporting recent guideline revisions.
  • To offer guidance on specific treatment and management challenges in NHL.

Main Methods:

  • Review of NCCN Guidelines for Non-Hodgkin's Lymphomas.
  • Analysis of clinical evidence supporting guideline changes.
  • Synthesis of recommendations for chronic lymphocytic leukemia and hepatitis virus management.

Main Results:

  • Updated recommendations for additional treatment options in chronic lymphocytic leukemia.
  • Guidance on managing hepatitis virus reactivation/infections in high-risk NHL patients.
  • Evidence-based support for the discussed guideline updates.

Conclusions:

  • The updated NCCN Guidelines offer enhanced treatment strategies for NHL patients.
  • Proactive management of hepatitis virus is essential for patients undergoing NHL therapy.
  • These insights aim to improve clinical decision-making in NHL care.