Related Experiment Video
Updated: Sep 26, 2026

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol
Published on: April 1, 2018
[Evoked potentials and the mode of cognitive development in boys 6 to 8 years of age presenting hyperactivity with
Insights
Children with attention deficit hyperactivity disorder (ADHD) showed distinct event-related potential patterns, specifically a larger P250 amplitude, compared to controls. Age-related differences in P350 latency were also observed, differing between groups and stimulus types.
Area of Science:
- Neuroscience
- Developmental Psychology
- Cognitive Science
Context:
- Event-related potentials (ERPs) offer insights into neural processing.
- Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder affecting attention and behavior.
- Childhood cognitive development involves distinct stages of information processing.
Purpose:
- To investigate differences in event-related potentials (ERPs) between children with ADHD and typically developing controls.
- To examine how different visual stimuli (pictures, words, figures, digits) affect ERPs in these groups.
- To explore age-related changes in ERPs and their relationship to cognitive development.
Summary:
- ERPs, specifically fronto-central P250 and parieto-occipital P350, were recorded during categorization tasks in 12 male children (6-8 years) with ADHD and 12 controls.
- The ADHD group exhibited a larger overall P250 amplitude.
- While P350 latency decreased with age in controls, with specific differences noted for word vs. picture stimuli in the left hemisphere, this pattern was absent in the ADHD group.
Impact:
- Findings suggest altered neural processing and orienting reactions in children with ADHD.
- The study highlights potential differences in cognitive development modes between ADHD and control groups.
- Results contribute to understanding the neurophysiological underpinnings of ADHD and its developmental trajectory.
Abstract:
Event-related potentials were recorded in 2 groups (attention deficit hyperactivity disorder--ADHD--and normal controls) of 12 male children aged between 6-8 years during 4 categorization tasks. Each task was performed with a different type of visual stimulus; pictures, words, geometrical figures or digits. The amplitudes and latencies of a fronto-central P250 and a parieto-occipital P350 were examined. The overall amplitude of the fronto-central P250 was larger in the ADHD group. However, the overall latency of the parieto-occipital P350 decreased with age; coincidentally, in the control group, the P350 latency measured in the left hemisphere became shorter with age for the words than for the pictures. This was not the case in the ADHD group. These results are discussed in relation to the level of the orienting reaction and the modes (general or differentiated) of cognitive development.
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