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Published on: June 2, 2019
Method of diagnosing pre-eclampsia
Steven J Wagner1, Vesna D Garovic
1Mayo Clinic, Division of Nephrology and Hypertension, 200 First Street SW, Rochester, Minnesota 55905, USA +1 507 284 3594 ; +1 507 284 1161 ; garovic.vesna@mayo.edu.
Abstract:
Pre-eclampsia is a pregnancy-specific disorder that causes a high degree of maternal and fetal morbidity and mortality. Despite many recent advances in the field, the diagnosis, treatment and prevention of pre-eclampsia remain elusive. The current patent application provides evidence for a marker of pre-eclampsia, a 26.6-kDa polypeptide, which is present in pre-eclamptic women and absent in normal controls. The prospect of developing a laboratory test for the diagnosis of pre-eclampsia is exciting, as is the possibility for risk-stratification and potential therapies.
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