Related Experiment Video
Updated: May 13, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
Published on: June 10, 2013
Symptoms of anxiety and depression in lesbian couples treated with donated sperm: a descriptive study
C Borneskog1, G Sydsjö, C Lampic
1Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. catrin.borneskog@kbh.uu.se
Objective:
To investigate symptoms of anxiety and depression in lesbian couples undergoing assisted reproductive treatment (ART), and to study the relationship of demographic data, pregnancy outcome and future reproductive plans with symptoms of anxiety and depression.
Design:
Descriptive, a part of the prospective longitudinal 'Swedish study on gamete donation'.
Setting:
All university clinics in Sweden performing gamete donation.
Population:
A consecutive sample of 214 lesbian couples requesting assisted reproduction, 165 of whom participated.
Methods:
Participants individually completed three study-specific questionnaires and the Hospital Anxiety and Depression Scale (HADS): time point 1 (T1), at commencement of ART; time point 2 (T2), approximately 2 months after treatment; and time point 3 (T3), 2-5 years after first treatment.
Main Outcome Measures:
Anxiety and depression (HADS), pregnancy outcome and future reproductive plans.
Results:
The vast majority of lesbian women undergoing assisted reproduction reported no symptoms of anxiety and depression at the three assessment points. A higher percentage of the treated women, compared with the partners, reported symptoms of anxiety at T2 (14% versus 5%, P = 0.011) and T3 (10% versus 4%, P = 0.018), as well as symptoms of depression at T2 (4% versus 0%, P = 0.03) and T3 (3% versus 0%, P = 0.035). The overall pregnancy outcome was high; almost three-quarters of lesbian couples gave birth 2-5 years after sperm donation treatments. Open-ended comments illustrated joy and satisfaction about family building.
Conclusion:
Lesbian women in Sweden reported good psychological health before and after treatment with donated sperm.
Related Concept Videos
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depression: Overview
Disorders of the Female Reproductive System
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...