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Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

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Published on: December 15, 2014

Semiautomatic estimation of breast density with DM-Scan software.

I Martínez Gómez1, M Casals El Busto2, J Antón Guirao3

  • 1Programa de Cribado de Cáncer de Mama de la Comunidad Valenciana, Unidad de Alzira, Alzira, Valencia, España.

Radiologia
|March 16, 2013
PubMed
Summary
This summary is machine-generated.

DM-Scan software offers more reproducible breast density calculations than visual inspection. This semiautomatic method reduces subjectivity and variability in assessing fibroglandular tissue density.

Keywords:
Breast cancerBreast densityComputer-assisted diagnosisCáncer de mamaDensidad mamariaDiagnóstico asistido por ordenadorDigital processing of mammogramsInterobserver variabilityIntraobserver variabilityMammographyMamografíaProcesamiento digital de mamografíasVariabilidad interobservadorVariabilidad intraobservador

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Last Updated: May 13, 2026

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Area of Science:

  • Radiology
  • Medical Imaging Analysis

Background:

  • Accurate breast density assessment is crucial for mammography interpretation and breast cancer risk stratification.
  • Visual estimation of breast density can be subjective and lead to inter-observer variability.

Purpose of the Study:

  • To evaluate the reproducibility of breast density calculation using DM-Scan software.
  • To compare the reproducibility of DM-Scan with traditional visual inspection methods.

Main Methods:

  • 655 direct digital mammograms were analyzed by three radiologists using DM-Scan software.
  • Inter- and intra-observer agreement for DM-Scan and visual inspection (Boyd and BI-RADS® scales) were calculated using intraclass correlation coefficient and Kappa index.

Main Results:

  • DM-Scan demonstrated higher mean inter- and intra-observer agreement (0.92) compared to visual inspection.
  • Visual inspection showed mean interobserver agreement of 0.876 (Boyd) and 0.823 (BI-RADS®).
  • Visual inspection showed mean intraobserver agreement of 0.813 (Boyd) and 0.770 (BI-RADS®).

Conclusions:

  • Semiautomatic breast density calculation with DM-Scan software is more reproducible than visual estimation.
  • DM-Scan software reduces subjectivity and variability in breast density determination.