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Bioresorbable scaffolds: talking about a new interventional revolution [corrected]
M E C J Hassell1, M J D Grundeken, R Delewi
1Department of Cardiology, University of Amsterdam, Amsterdam, The Netherlands.
Minerva Cardioangiologica
|March 16, 2013
Summary
Fully bioresorbable scaffolds (BRS) represent a potential revolution in cardiology, offering transient support without permanent metal implants. Further research is needed to confirm their long-term benefits and suitability for complex cases.
Area of Science:
- Interventional Cardiology
- Biomaterials Science
Background:
- Metallic stents, including bare-metal and drug-eluting stents, have advanced cardiac interventions.
- Fully bioresorbable scaffolds (BRS) aim to provide transient vessel support, potentially overcoming limitations of permanent metallic stents.
Purpose of the Study:
- To review clinically evaluated fully bioresorbable scaffolds (BRS).
- To provide an overview of ongoing clinical studies involving BRS.
- To assess the potential of BRS as the next revolution in interventional cardiology.
Main Methods:
- Literature review of BRS technology.
- Analysis of clinical evaluations and ongoing studies of BRS.
Main Results:
- BRS offer acute gain and prevent vessel occlusion, similar to metallic stents.
- BRS may allow for long-term vessel remodeling and plaque regression without a permanent metallic cage.
- Several BRS have been developed and are undergoing clinical evaluation.
Conclusions:
- BRS technology shows promise for interventional cardiology.
- More extensive studies, particularly in complex lesions, are required to establish BRS in routine clinical practice.
- The long-term efficacy and safety of BRS need further validation to confirm their revolutionary potential.
