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Updated: May 13, 2026

Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues
Published on: June 3, 2016
An epigenetic roadmap for cardiomyocyte differentiation
Michael S Parmacek1, Jonathan A Epstein
1Cardiovascular Institute, Department of Medicine, Institute for Regenerative Medicine and the Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Abstract:
Wamstad et al have provided a robust global analysis of histone markers and gene expression at 4 stages of murine embryonic stem (ES) cell differentiation into cardiac myocytes. This detailed data set will provide a rich opportunity for generating and testing hypotheses related to combinatorial transcriptional regulation of gene expression and epigenetic regulation of cell fate decisions in cardiac lineages.
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