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Updated: May 13, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Computational fluid dynamics simulation of an anterior communicating artery ruptured during angiography
Simona Hodis1, Susheil Uthamaraj, Giuseppe Lanzino
1Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Abstract:
We present a computational fluid dynamics (CFD) analysis of the hemodynamic environment of an anterior communicating artery that spontaneously ruptured immediately following three-dimensional rotational angiography. Subsequent digital subtraction angiography allowed for the localization of the point of rupture within the aneurysm dome. CFD analysis demonstrated a concentrated jet that impinged directly at the site of rupture. Peak systolic pressure and wall shear stress were both maximal near the rupture location.
