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Updated: May 13, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Radiation-induced sarcoma in spine.

Lok Sang Kam¹, Marina Portia Anthony, H Shek

¹The University of Hong Kong, Hong Kong, China.

Polish Journal of Radiology

|March 16, 2013

Summary

Radiotherapy for cancer can rarely cause secondary bone cancers. This case highlights a radiation-induced fibrosarcoma in the spine, a rare but recognized late complication.

Area of Science:

Oncology
Radiation Oncology
Skeletal Radiology

Background:

Radiotherapy is a cornerstone of cancer treatment.
Late complications of radiotherapy can include secondary malignancies.
Radiation-induced sarcomas (RIS) are a known, though uncommon, complication.

Observation:

This report details a rare case of radiation-induced fibrosarcoma.
The tumor arose in the T1 lamina and spinous process.
The patient had a history of breast cancer treated with radiotherapy 30 years prior.

Findings:

Radiation-induced sarcoma in the spine is not well-recognized.
This case underscores the potential for spinal bone sarcomas years after radiation therapy.
Fibrosarcoma developed in the irradiated spinal region.

Keywords:

fibrosarcoma radiation radiotherapy sarcoma spine

Related Experiment Videos

Last Updated: May 13, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Implications:

Awareness of spinal radiation-induced sarcomas is crucial for clinicians.
Long-term surveillance may be warranted in patients with a history of radiotherapy.
This case contributes to the understanding of rare oncologic complications.