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Psychosis from subthalamic nucleus deep brain stimulator lesion effect
Alik S Widge1, Pinky Agarwal, Monique Giroux
1Department of Psychiatry, University of Washington, Seattle, USA.
Surgical Neurology International
|March 16, 2013
Summary
Psychosis can occur after subthalamic nucleus deep brain stimulation (DBS) for Parkinson's disease (PD) due to tissue reaction, even before stimulation begins. This effect may allow safe use of certain medications in PD patients.
Area of Science:
- Neuroscience
- Neurosurgery
- Psychiatry
Background:
- Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective for Parkinson's disease (PD) symptoms.
- However, STN-DBS can cause psychiatric side effects like psychosis, with unclear causes.
- Effective management strategies for these side effects are needed.
