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Abstract:
Dose-response curves of the lesions yield and cell survival rate are obtained for radiation intensity stochastic in time. It was shown that, by analogy with the microdosimetric description, the quadratic dependence, that presents the lesions yield as a function of radiation intensity within the high dose range, is to produce a linear-quadratic dose response. The appearance of a linear component is conditioned by the correlativity of radiation. The asymptotic values are obtained for a single-hit scheme survival rate in the cases of prolonged and pulse irradiation.