Electrospinning tubular scaffolds with tissue-like mechanical properties and biomimetic surface features

Electrospinning is a useful technique for generating scaffolds composed of nano- and/or microfibers. Through an innovative modification of the cylindrical target mandrel it is possible to create macrostructural or microstructural invaginations. The former provides complex bulk mechanical behavior reminiscent of native soft tissue; the latter leads to a surface topography reminiscent of intestinal villi.