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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Fluid-attenuated inversion recovery vascular hyperintensities are not visible using 3D CUBE FLAIR sequence.
Jérôme Hodel1, Xavier Leclerc, Mathieu Rodallec
1Department of Radiology, Hôpital Saint Joseph, Paris, France. jeromehodel@hotmail.com
European Radiology
|March 16, 2013
Summary
Fluid-attenuated inversion recovery (FLAIR) vascular hyperintensities (FVH) are crucial markers for acute ischaemic stroke. However, 3D CUBE FLAIR MRI sequences are not sensitive for detecting FVH, unlike conventional 2D FLAIR images.
Area of Science:
- Neuroradiology
- Neuroimaging
Background:
- Fluid-attenuated inversion recovery (FLAIR) vascular hyperintensities (FVH) are significant imaging markers in acute ischaemic stroke.
- FVH were initially described using 2D FLAIR sequences.
Purpose of the Study:
- To compare the sensitivity of 3D CUBE FLAIR sequences versus 2D FLAIR for detecting FVH.
- To evaluate the utility of 3D CUBE FLAIR in acute ischaemic stroke assessment.
Main Methods:
- Forty-seven patients with suspected stroke underwent both 2D and 3D CUBE FLAIR MRI.
- Three blinded readers assessed for FVH, acute infarcts, and arterial stenosis.
- Reader agreement was evaluated.
Main Results:
- FVH were detected on 2D FLAIR in 15 patients, often co-occurring with acute brain infarct or arterial stenosis.
- No FVH were visualized on 3D CUBE FLAIR images, regardless of location.
- Excellent agreement was observed among readers.
Conclusions:
- 3D CUBE FLAIR sequences are not suitable for visualizing FVH.
- Conventional 2D FLAIR images remain the standard for assessing FVH in suspected acute ischaemic stroke.
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