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Updated: May 13, 2026
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Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
Published on: March 3, 2023
Repeat hepatectomy for recurrent colorectal metastases.
D A Wicherts1, R J de Haas, C Salloum
1Department of Surgery, Assistance Publique-Hôpitaux de Paris Hôpital Paul Brousse, Centre Hépato-Biliaire, Villejuif, France.
The British Journal of Surgery
|March 16, 2013
Summary
Repeat hepatectomy for colorectal metastases offers long-term survival benefits in select patients. This procedure shows comparable morbidity to initial liver resection, with improved survival rates for those undergoing repeat operations.
Area of Science:
- Hepatobiliary surgery
- Surgical oncology
- Gastrointestinal oncology
Background:
- The oncological benefit of repeat hepatectomy for recurrent colorectal metastases remains uncertain.
- This study evaluates the efficacy of repeat hepatectomy within contemporary multidisciplinary treatment protocols.
Purpose of the Study:
- To assess the oncological value and outcomes of repeat hepatectomy for patients with recurrent colorectal metastases.
- To compare the postoperative outcomes and survival rates of patients undergoing repeat hepatectomy versus a single hepatectomy.
Main Methods:
- A retrospective analysis of consecutive patients who underwent repeat hepatectomy for colorectal metastases between 1990 and 2010.
- Exclusion of patients who underwent two-stage hepatectomy.
- Comparison of postoperative outcomes and survival data between patients with single and repeat hepatectomies.
Main Results:
- Repeat hepatectomy (second, third, or fourth) had similar postoperative morbidity compared to initial liver resection.
- Postoperative mortality was slightly higher after repeat hepatectomy (3.1%) versus first hepatectomy (1.6%).
- Three- and 5-year survival rates were significantly higher in patients who underwent repeat hepatectomy (76% and 54%) compared to those with a single hepatectomy (58% and 45%). Repeat hepatectomy between 2000-2010 was an independent predictor of longer survival.
Conclusions:
- Repeat hepatectomy is a viable option for selected patients with recurrent colorectal metastases.
- This procedure can offer significant long-term survival advantages in carefully chosen patient cohorts.
