Related Experiment Video
Updated: May 13, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Diagnosis and treatment of invasive group A streptococcal infections
Andrew C Steer1, Nigel Curtis, Jonathan R Carapetis
1Clinical and Public Health Research Fellow University of Melbourne, Centre for International Child Health, Department of Paediatrics, Royal Children's Hospital Melbourne, Flemington Road, Parkville, Victoria, 3052, Australia +613 9345 5522 ; +613 9345 6667 ; andrew.steer@rch.org.au.
Background:
Invasive group A streptococcal infections are serious infections that carry a high mortality.
Objective:
The aim was to review current methods of diagnosis and treatment of invasive group A streptococcal infections as well as to provide background on the pathogenesis and epidemiology of these infections.
Methods:
The most recent literature regarding pathogenesis, epidemiology, diagnosis and treatment of invasive group A streptococcal infections is reviewed.
Results/Conclusion:
The incidence of invasive group A streptococcal infections in industrialised countries is in the order of 3 per 100,000, whereas in developing countries available evidence suggests that the incidence is several-fold higher. Management of invasive group A streptococcal infections includes supportive care, surgical debridement of necrotic tissue, correct use of antibiotics, intravenous immunoglobulin and contact prophylaxis. Recent studies suggest that the early use of intravenous immunoglobulin may reduce the need for radical debridement of tissue in cases of necrotising fasciitis.
Related Concept Videos
Rheumatic Heart Disease III: Medical Management
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Staphylococcal Skin Infections
Mitral Stenosis III: Medical Management
Endocarditis III: Medical Management