Related Experiment Video
Updated: May 13, 2026

11:28
Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
Diagnostic markers for hepatitis virus infection.
Prista Charuworn1, Ramsey Cheung
1Stanford University School of Medicine, Division of Gastroenterology and Hepatology, Stanford, CA 94305, USA.
Expert Opinion on Medical Diagnostics
|March 19, 2013
Summary
Recent diagnostic advances for viral hepatitis A-D improve patient care and blood safety. Enhanced serologic and molecular tests aid in understanding disease, guiding treatment, and ensuring safer blood supplies.
Area of Science:
- Hepatology
- Virology
- Infectious Diseases
Background:
- Accurate diagnosis and characterization of hepatitis viruses are crucial for public health and clinical decision-making.
- Understanding viral hepatitis epidemiology and pathogenesis is essential for effective control strategies.
Purpose of the Study:
- To review recent advancements in the diagnosis of viral hepatitis A, B, C, and D.
- To assess the clinical utility of novel diagnostic methods for viral hepatitis.
Main Methods:
- Comprehensive literature review of studies published up to 2007.
- Focus on serologic and molecular diagnostic techniques for hepatitis viruses.
Main Results:
- Recent improvements in diagnostic test sensitivity and ease of use.
- Enhanced understanding of viral hepatitis natural history and disease progression.
- Improved pretreatment evaluation and guidance for antiviral therapy.
Conclusions:
- Advances in diagnostics enhance clinical management of viral hepatitis.
- Increased reliance on improved diagnostic technologies will bolster blood supply safety.
- Future technological improvements promise further expansion of diagnostic test roles in patient care.
Related Concept Videos
Hepatitis
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction
Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...

