Related Experiment Video
Updated: May 13, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
Published on: May 16, 2021
Future trends in screening technology for drug discovery
1Department of Molecular Screening and Cellular Pharmacology, Serono Pharmaceutical Research Institute, Ch. les Aulx 14, 1228 Plan-les-Ouates, Geneva, CH. Switzerland. Alexander.Scheer@serono.com.
Abstract:
The last decade showed a further upsurge in screening technology advance and innovation. Notably, the establishment of ultra high-throughput screening facilities led to an explosion of screening capacities. However, in the last 2 years, a turning point in screening philosophy can be observed worldwide. Increasingly more companies are reducing the size of screening campaigns, while increasing the emphasis on data quality and relevance. This article tries to investigate how screening technologies will develop in the ever-changing landscape of drug discovery.
Related Concept Videos
Drug Discovery: Overview
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Patch Clamp
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
Pharmacogenomics: Identification of New Drug Targets

