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Quantitative Polymerase Chain Reaction (qPCR)-Based Rapid Diagnosis of Helicobacter pylori Infection and Antibiotic Resistance
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Progress in developing accurate tests for the diagnosis of Helicobacter pylori infection

Ozlem Yilmaz1

  • 1Dokuz Eylül University, Faculty of Medicine, Department of Microbiology and Clinical Microbiology, 35340, Inciralti, ˙Izmir, Turkey +90 232 412 45 06 ; +90 232 259 05 41 ; ozlem.yilmaz@deu.edu.tr.

Expert Opinion on Medical Diagnostics
|March 19, 2013
PubMed

Insights

Helicobacter pylori (H. pylori) is a stomach pathogen linked to ulcers and cancer. Its role in functional dyspepsia requires further investigation, despite being the only known microbe in the human stomach.

Area of Science:

  • Gastroenterology
  • Microbiology
  • Infectious Diseases

Background:

  • Helicobacter pylori (H. pylori) is a significant bacterial pathogen.
  • It is the primary cause of gastritis, peptic ulcers, gastric cancer, and MALT lymphoma.
  • H. pylori uniquely colonizes the human gastric mucosa.

Purpose of the Study:

  • To explore the role of H. pylori infection in functional dyspepsia.
  • To highlight the known pathogenic roles of H. pylori in gastroduodenal diseases.

Main Methods:

  • Detection of H. pylori infection using non-invasive methods.
  • Detection of H. pylori infection using invasive methods, including endoscopy.

Main Results:

  • Chronic H. pylori infection is a recognized risk factor for gastroduodenal diseases.
  • The specific contribution of H. pylori to functional dyspepsia remains under-explored.

Conclusions:

  • H. pylori is a major cause of significant gastroduodenal pathology.
  • Further research is needed to elucidate the relationship between H. pylori and functional dyspepsia.

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