Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Urine PD-L1 as a non-invasive biomarker for immune checkpoint inhibitor (ICI) therapy in bladder cancer.

Advances in biomarker sciences and technologyยท2026
Same author

Advances in Precision Diagnostics: The Emerging Role of Digital Pathology and Artificial Intelligence.

Advances in anatomic pathologyยท2026
Same author

Incidence, Clinicopathologic Features, and Follow-up Results of Invasive Ductal Carcinoma With Lobular-Like Growth Pattern.

Clinical breast cancerยท2026
Same author

Advances in Digital Cytopathology and Artificial Intelligence Applications.

Advances in anatomic pathologyยท2026
Same author

Pixelomics: The Omics-Style Interrogation of Whole Slide Images for Precision Pathology.

Advances in anatomic pathologyยท2026
Same author

Updates on Digital Pathology and Artificial Intelligence for Clinical Applications in Surgical Pathology.

Advances in anatomic pathologyยท2026
Same journal

Evaluation and management of pulmonary nodules: state-of-the-art and future perspectives.

Expert opinion on medical diagnosticsยท2013
Same journal

Biomarkers in IgA nephropathy: relationship to pathogenetic hits.

Expert opinion on medical diagnosticsยท2013
Same journal

The molecular landscape of diffuse glioma and prospects for biomarker development.

Expert opinion on medical diagnosticsยท2013
Same journal

Difficulties and barriers in diagnosing Fabry disease: what can be learnt from the literature?

Expert opinion on medical diagnosticsยท2013
Same journal

Promising biomarkers for systemic lupus erythematosus.

Expert opinion on medical diagnosticsยท2013
Same journal

Challenges of COPD diagnosis.

Expert opinion on medical diagnosticsยท2013
See all related articles

Related Experiment Video

Updated: May 13, 2026

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System
09:33

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System

Published on: May 3, 2018

Automated whole slide imaging.

Waqas Amin1, S Joseph Srintrapun, Anil V Parwani

  • 1University of Pittsburgh School of Medicine, Department of Biomedical Informatics, Pittsburgh, PA 15232, USA.

Expert Opinion on Medical Diagnostics
|March 19, 2013
PubMed
Summary
This summary is machine-generated.

Automated whole slide imaging (WSI) systems are robotic microscopes that digitize pathology slides. These systems offer improved image quality and editing functions, enhancing efficiency in slide assessment.

More Related Videos

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues
07:40

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues

Published on: May 1, 2019

Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment
13:01

Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment

Published on: June 3, 2022

Related Experiment Videos

Last Updated: May 13, 2026

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System
09:33

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System

Published on: May 3, 2018

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues
07:40

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues

Published on: May 1, 2019

Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment
13:01

Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment

Published on: June 3, 2022

Area of Science:

  • Digital Pathology
  • Medical Imaging Technology

Background:

  • Whole slide imaging (WSI) technology is increasingly adopted in pathology.
  • Advancements in computing speed, networking, and image quality drive WSI adoption.
  • WSI offers potential for reduced turnaround times in slide assessment.

Purpose of the Study:

  • To review the structure, functioning, and performance of commercially available WSI systems.
  • To highlight validation studies assessing the utility of WSI systems.

Main Methods:

  • Review of market-available WSI systems.
  • Analysis of validation studies for WSI utility.

Main Results:

  • Commercially available WSI systems provide robotic microscopy for full slide digitization.
  • Software enables merging of fields into composite images with enhanced editing and quality functions.

Conclusions:

  • Automated WSI systems digitize entire slides field by field.
  • Commercial WSI systems offer improved functions for digital image editing and quality enhancement.