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Published on: July 28, 2018
How to optimize the benefits of computer assisted sperm analysis in experimental toxicology
Carsten Schleh1, Anne-Laure Leoni
1Department of in vivo Pharmacology / Toxicology, BSL BIOSERVICE Scientific Laboratories GmbH, Behringstr, 6 / 8, Planegg/Munich 82152, Germany. cschleh@bioservice.com.
Abstract:
Exposure at the working place to various substances, that may affect semen quality is possible and should be investigated in detail. One appropriate method for this is computer-assisted sperm analysis (CASA) which offers multiple benefits in comparison to manual evaluation. However, several pitfalls exist, which make the evaluation of data obtained from CASA difficult to interpret. In the present commentary, we focus on these problems, show some examples, and try to define minimum standards which should be taken into consideration whenever working with computer-assisted sperm analysis.

