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Updated: May 13, 2026

Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
Wound management and nutrition for optimal wound healing
Steven V Dryden1, William G Shoemaker, Jae H Kim
1Division of Oral and Maxillofacial Surgery, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889, USA. steven.dryden@us.army.mil
Abstract:
The process of wound healing is complicated and requires optimization of wound bed conditions locally through wound management and systemically through proper nutritional care. Although there are a variety of local and systemic factors that can adversely influence healing, the wound environment can be treated through proper dressings to decrease necrotic debris, bacterial load, and foreign bodies. In addition, maintaining or improving patient nutritional status will help the body to supply the necessary building blocks and cellular response for healing to take place.
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