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Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation
Published on: June 26, 2018
Default mode network functional connectivity altered in failed back surgery syndrome
Jennifer Kornelsen1, Uta Sboto-Frankenstein, Theresa McIver
1Magnetic Resonance Technology, Institute for Biodiagnostics, National Research Council Canada, Winnipeg, Canada. jennifer.kornelsen@nrc-cnrc.gc.ca
Unlabelled:
The purpose of this study was to identify alterations in the default mode network of failed back surgery syndrome patients as compared to healthy subjects. Resting state functional magnetic resonance imaging was conducted at 3 Tesla and data were analyzed with an independent component analysis. Results indicate an overall reduced functional connectivity of the default mode network and recruitment of additional pain modulation brain regions, including dorsolateral prefrontal cortex, insula, and additional sensory motor integration brain regions, including precentral and postcentral gyri, for failed back surgery syndrome patients.
Perspective:
This article presents alterations in the default mode network of chronic low back pain patients with failed back surgery syndrome as compared to healthy participants.
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