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Updated: May 13, 2026

Salinity-dependent Toxicity Assay of Silver Nanocolloids Using Medaka Eggs

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Published on: March 18, 2016

Heavy metals affect regulatory volume decrease (RVD) in nematocytes isolated from the jellyfish Pelagia noctiluca.

R Morabito¹, A Marino, G La Spada

¹Dept. of Human and Social Sciences, University of Messina, Italy.

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology

|March 19, 2013

Summary

This summary is machine-generated.

Heavy metals like copper, cadmium, and zinc disrupt jellyfish stinging cells

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Quantification of Heavy Metals and Other Inorganic Contaminants on the Productivity of Microalgae

Quantification of Heavy Metals and Other Inorganic Contaminants on the Productivity of Microalgae

Published on: July 10, 2015

Area of Science:

Ecotoxicology
Marine Biology
Cell Physiology

Background:

Environmental contamination by heavy metals poses risks to biological systems.
Cnidarians, with specialized stinging cells (nematocytes), serve as valuable bio-indicators for toxicological effects.
Nematocytes exhibit distinct osmotic responses: an acute osmotic phase (OP) and a regulatory volume decrease (RVD) phase.

Purpose of the Study:

To investigate the impact of heavy metals (Cd, La, Co, Cu, Zn) on nematocyte osmotic responses (OP and RVD).
To assess the potential of Cnidarian nematocytes as ecotoxicological models.

Main Methods:

Isolated nematocytes from the jellyfish Pelagia noctiluca were exposed to artificial sea water containing varying concentrations of heavy metals (0.1–100 μM).
The effects on osmotic phase (OP) and regulatory volume decrease (RVD) were measured.

Main Results:

Cobalt (Co) and Lanthanum (La) inhibited RVD but not OP.
Copper (Cu), Cadmium (Cd), and Zinc (Zn) prevented OP in a dose-dependent manner, consequently inhibiting RVD.
Heavy metals interfere with OP and/or RVD in isolated nematocytes.

Conclusions:

Heavy metal pollutants impair nematocyte RVD, either directly or by interfering with OP.
Nematocytes demonstrate sensitivity to heavy metal toxicity, supporting their use in ecotoxicological studies.
Further research is needed to elucidate the precise mechanisms of heavy metal toxicity in these cells.