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Correction of glottic insufficiency by collagen injection
M Remacle1, E Marbaix, M Hamoir
1Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital of Mont-Godinne, University of Louvain, Yvoir, Belgium.
The Annals of Otology, Rhinology, and Laryngology
|June 1, 1990
Summary
GAX collagen offers vocal fold augmentation results comparable to Zyderm Collagen II. GAX collagen provides better resistance to collagenase and less hypersensitivity, avoiding overcorrection.
Area of Science:
- Otolaryngology
- Biomaterials Science
- Regenerative Medicine
Background:
- Vocal fold augmentation is crucial for voice restoration.
- Current injectable collagen fillers have limitations.
- GAX collagen presents a novel alternative for vocal fold augmentation.
Purpose of the Study:
- To evaluate the efficacy and safety of GAX collagen for vocal fold augmentation.
- To compare GAX collagen with Zyderm Collagen II (ZCI).
Main Methods:
- Thirty-nine patients underwent vocal fold augmentation using GAX collagen.
- Objective assessments included maximum phonation time, phonatory quotient, vocal frequency analysis, and laryngostroboscopy.
Main Results:
- GAX collagen demonstrated objective results comparable to Zyderm Collagen II.
- Key advantages of GAX collagen include avoidance of overcorrection, enhanced resistance to collagenase, and reduced hypersensitivity.
Conclusions:
- GAX collagen is a viable and effective option for vocal fold augmentation.
- GAX collagen offers distinct advantages over Zyderm Collagen II, improving patient outcomes and treatment tolerability.