Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

7.4K
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
7.4K
Physiological Control of Respiration01:23

Physiological Control of Respiration

5.8K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
5.8K
Blood Pressure Imbalances and Circulatory Shock01:24

Blood Pressure Imbalances and Circulatory Shock

1.5K
Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
1.5K
Control Systems01:10

Control Systems

1.8K
Control systems are everywhere in contemporary society, influencing diverse applications from aerospace to automated manufacturing. These systems can be found naturally within biological processes, such as blood sugar regulation and heart rate adjustment in response to stress, as well as in man-made systems like elevators and automated vehicles. A control system is essentially a network of subsystems and processes that collaboratively convert specific inputs into desired outputs.
At the heart...
1.8K
Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

6.8K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
6.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward the constructive theory of human social behavior. I. General principles.

Annals of the New York Academy of Sciences·1992
Same author

Toward the constructive theory of human social behavior. II. Consumer behavior.

Annals of the New York Academy of Sciences·1992
Same author

Toward the constructive theory of human social behavior. III. Labor behavior with due regard for consumption.

Annals of the New York Academy of Sciences·1992
Same author

Toward the constructive theory of human social behavior. IV. Labor behavior under fixed remuneration.

Annals of the New York Academy of Sciences·1992
Same author

Toward the constructive theory of human social behavior. V. Labor behavior under piecework pay.

Annals of the New York Academy of Sciences·1992
Same journal

Large-Eddy Simulation of the FDA Benchmark Blood Pump: Validation Against Experiments and Implications for Turbulent Flow Mechanisms.

Artificial organs·2026
Same journal

The Warm Revolution: A Meta-Analysis of DCD Versus DBD Liver Transplant Outcomes in the Normothermic Machine Perfusion Era.

Artificial organs·2026
Same journal

Toward Optimal Remote Monitoring in LVAD Recipients: Remaining Challenges Beyond Feasibility.

Artificial organs·2026
Same journal

Advancing Organ Preservation and Perfusion: Introducing the International Society of Organ Preservation and Perfusion Therapy (ISOPPT).

Artificial organs·2026
Same journal

Short Inter-Treatment Interval Treatment With Artificial Liver Support System Reduces 90-Day Transplant-Free Mortality in Patients With Hepatitis B Virus-Related Acute-On-Chronic Liver Failure: A Retrospective Observational Study.

Artificial organs·2026
Same journal

Extracorporeal Albumin Dialysis (OPAL) as Novel Therapeutic Bridging Option in Posthepatectomy Liver Failure.

Artificial organs·2026
See all related articles

Related Experiment Videos

Artificial blood circulation: stabilization, physiological control, and optimization.

A Y Lerner1

  • 1Faculty of Mathematical Sciences, Weizmann Institute of Science, Rehovot, Israel.

Artificial Organs
|April 1, 1990
PubMed
Summary
This summary is machine-generated.

An efficient Artificial Blood Circulation System (ABCS) requires a three-level adaptive control. This system stabilizes circulation, coordinates pumps, and optimizes physiological control for metabolism and varying body conditions.

Related Experiment Videos

Area of Science:

  • Biomedical Engineering
  • Control Systems Engineering
  • Physiology

Background:

  • Artificial Blood Circulation Systems (ABCS) are crucial for supporting cardiovascular function.
  • Efficient operation requires sophisticated control to manage complex physiological parameters.
  • Existing systems face challenges in adapting to dynamic patient conditions and metabolic demands.

Purpose of the Study:

  • To define the requirements for an efficient Artificial Blood Circulation System (ABCS).
  • To propose a hierarchical three-level adaptive control system for ABCS.
  • To address key challenges including circulation stabilization, pump coordination, and physiological regulation.

Main Methods:

  • Development of a hierarchical three-level adaptive control system architecture.
  • Utilizing real-time computer-processed signals correlating hydraulic resistance/aortic pressure with gas exchange.
  • Implementing adaptive algorithms to manage varying load and body parameters.

Main Results:

  • The proposed control system effectively stabilizes circulation conditions.
  • Coordination between left and right artificial pumps is achieved.
  • Physiological control is maintained, balancing cardiac output with metabolic gas exchange needs.
  • System behavior is optimized for adaptability to changing physiological states.

Conclusions:

  • A hierarchical three-level adaptive control system is essential for efficient ABCS.
  • This control strategy successfully addresses critical aspects of artificial circulation.
  • The system demonstrates adaptability to dynamic physiological and external conditions.