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Updated: May 13, 2026

The Participant-Reported Implementation Update and Score (PRIUS): A Novel Method for Capturing Implementation-Related Data Over Time
Published on: February 19, 2021
Methodology issues in implementation science
Robin Newhouse1, Kathleen Bobay, Patricia C Dykes
1Organizational Systems and Adult Health, University of Maryland School of Nursing, Baltimore, MD 21201, USA. newhouse@son.umaryland.edu
Background:
Putting evidence into practice at the point of care delivery requires an understanding of implementation strategies that work, in what context and how.
Objective:
To identify methodological issues in implementation science using 4 studies as cases and make recommendations for further methods development.
Research Design:
Four cases are presented and methodological issues identified. For each issue raised, evidence on the state of the science is described.
Results:
Issues in implementation science identified include diverse conceptual frameworks, potential weaknesses in pragmatic study designs, and the paucity of standard concepts and measurement.
Conclusions:
Recommendations to advance methods in implementation include developing a core set of implementation concepts and metrics, generating standards for implementation methods including pragmatic trials, mixed methods designs, complex interventions and measurement, and endorsing reporting standards for implementation studies.
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