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Clinical features and outcome in hospitalized heart failure in Japan (from the ATTEND Registry)

Naoki Sato1, Katsuya Kajimoto, Takehiko Keida

  • 1Internal Medicine and Cardiology, Nippon Medical School Musashi-Kosugi Hospital, Kawasaki, Japan. nms-ns@nms.ac.jp

Circulation Journal : Official Journal of the Japanese Circulation Society
|March 19, 2013
PubMed

Insights

Hospitalized heart failure in Japan affects many elderly patients, often with hypertension. This study analyzed 4,842 patients, revealing long hospital stays and high mortality, necessitating improved prevention and treatment strategies.

Area of Science:

  • Cardiology
  • Public Health
  • Clinical Research

Background:

  • Hospitalized heart failure (HHF) presents a significant challenge in Japan.
  • Improving HHF management and outcomes requires analysis of clinical features, in-hospital care, and patient results.

Purpose of the Study:

  • To analyze the clinical features, in-hospital management, and outcomes of patients with hospitalized heart failure in Japan.
  • To inform and improve clinical guidelines for HHF management.

Main Methods:

  • Utilized data from the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, the largest study of HHF in Japan.
  • Included 4,842 enrolled patients, focusing on clinical characteristics and in-hospital treatment.

Main Results:

  • The study population consisted primarily of elderly patients with new-onset heart failure, often with a history of hypertension and orthopnea.
  • Common treatments included furosemide and carperitide, with a mean length of stay of 30 days and an in-hospital mortality rate of 6.4%.

Conclusions:

  • Primary prevention of HHF is crucial for elderly hypertensive and diabetic patients.
  • Intensified management, including noninvasive positive pressure ventilation, is recommended during the acute phase.
  • Further research is needed to clarify the clinical benefits of carperitide and angiotensin-receptor blockers in the Japanese HHF population.
  • The relationship between length of stay and in-hospital mortality, considering both outcomes and costs, requires further investigation.
Abstract

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