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Updated: May 13, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Weight loss before conception: A systematic literature review.

Elisabet Forsum¹, Anne Lise Brantsæter, Anna-Sigrid Olafsdottir

¹Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Food & Nutrition Research

|March 19, 2013

Summary

Pre-conception weight loss in obese women may reduce risks like gestational diabetes and large-for-gestational-age infants. However, research on dietary interventions for weight loss before pregnancy is limited, necessitating alternative strategies.

Keywords:

gestational diabetes large-for-gestational-age-infants systematic review weight loss before pregnancy

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Area of Science:

Reproductive Health
Maternal Nutrition
Obesity Research

Background:

Rising rates of overweight and obesity in women present significant risks for adverse pregnancy outcomes.
High pre-conception body mass index (BMI) is an independent risk factor for maternal and infant complications.
Dietary counseling for pre-conception weight loss is recommended, but potential risks exist.

Purpose of the Study:

To systematically review and assess the effects of pre-conception weight loss on maternal and offspring health outcomes.
To evaluate studies published between January 2000 and December 2011 on weight loss interventions prior to conception.

Main Methods:

Systematic literature review of studies on pre-conception weight loss in overweight/obese women.
Initial search yielded 486 citations; 58 selected for full-text review.
Fifteen studies underwent quality assessment, with two included in evidence tables.

Main Results:

Limited evidence suggests pre-conception weight loss may reduce the risk of gestational diabetes.
One study indicated a reduced risk of large-for-gestational-age infants with pre-conception weight loss in women with BMI > 25.
No studies specifically investigated the effects of dietary interventions for weight loss prior to conception.

Conclusions:

There is a significant lack of research on the impact of dietary-induced pre-conception weight loss on maternal and infant health.
Conducting such studies is challenging, highlighting the need for alternative approaches.
Alternative strategies for weight management in women of reproductive age are required.