Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intracranial efficacy of combined immune checkpoint inhibitors and platinum plus etoposide therapy in patients with extensive-disease small-cell lung cancer and brain metastases.

Cancer treatment and research communications·2026

Same author

An index of maximal expiratory flow-volume curve with different features related to central and peripheral concavity.

ERJ open research·2026

Same author

Long-Term Survival Achieved by Combined Surgical Resection and Immunotherapy for Recurrent Adrenal Oligometastasis of Lung Adenocarcinoma: A Case Study.

Cureus·2026

Same author

Mitochondria-Dependent Metabolic Reprogramming Enhances Myofibroblast Differentiation and Aggravates Bleomycin-Induced Pulmonary Fibrosis.

Cells·2026

Same author

A Case of Tegafur-Uracil-Induced Interstitial Lung Disease Presenting as Hypersensitivity Pneumonitis.

Cureus·2026

Same author

The Nrf2-SLPI axis in aging and its role in the pathophysiology of pulmonary <i>Mycobacterium avium</i> complex disease.

Frontiers in immunology·2026

Same journal

Inflammasomes in Intestinal Inflammation: Guardians of Mucosal Homeostasis, Amplifiers of Disease, and Targets for Intervention.

Internal medicine (Tokyo, Japan)·2026

Same journal

Late-diagnosed Nonclassical 21-hydroxylase Deficiency in Two Elderly Men with Adrenal Incidentalomas: Clinical Clues to the Underlying Diagnosis.

Internal medicine (Tokyo, Japan)·2026

Same journal

Fish Bone Aspiration Presenting as Chronic Cough and Mimicking Asthma.

Internal medicine (Tokyo, Japan)·2026

Same journal

Successful Alternate-day Osimertinib Administration with Desensitization Following Osimertinib-induced Hepatotoxicity and Neutropenia in a Case of EGFR-mutant Lung Cancer.

Internal medicine (Tokyo, Japan)·2026

Same journal

Marked Hyperbilirubinemia in a Patient with Intrahepatic Cholestasis of Pregnancy and a UGT1A1 Polymorphism: A Case Report.

Internal medicine (Tokyo, Japan)·2026

Same journal

Successful Postpartum CAR T-cell Salvage Therapy for Primary Mediastinal Large B-cell Lymphoma with Residual Disease after R-CHOP During Pregnancy.

Internal medicine (Tokyo, Japan)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 13, 2026

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Published on: December 27, 2024

Defecation-related asthma.

Satoshi Ano¹, Yuko Morishima, Yukio Ishii

¹Department of Respiratory Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan.

Internal Medicine (Tokyo, Japan)

|March 19, 2013

Summary

This summary is machine-generated.

This case study highlights a unique asthma presentation linked to gastrointestinal distress. Prophylactic laxative use effectively managed asthma exacerbations triggered by the urge to defecate.

Related Experiment Videos

Last Updated: May 13, 2026

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Published on: December 27, 2024

Area of Science:

Pulmonology
Gastroenterology
Clinical Case Study

Background:

Recurrent asthma exacerbations can be triggered by various factors.
Gastrointestinal symptoms, such as abdominal cramps and defecation urge, are not typically associated with asthma.
A case of asthma linked to gastrointestinal distress is presented.

Purpose of the Study:

To report a unique case of asthma exacerbations associated with gastrointestinal symptoms.
To explore potential mechanisms linking gastrointestinal distress to bronchospasm.
To evaluate the efficacy of laxative treatment for this specific asthma phenotype.

Main Methods:

Case report of a 39-year-old male patient.
Detailed medical history including asthma and gastrointestinal symptoms.
Assessment of treatment response to anticholinergics and laxatives.

Main Results:

The patient experienced recurrent asthma attacks preceded by abdominal cramps and urge to defecate.
Anticholinergic medications were ineffective in managing the exacerbations.
Prophylactic use of laxatives led to significant symptom improvement.

Conclusions:

Asthma exacerbations can be linked to gastrointestinal symptoms in rare cases.
Increased parasympathetic tone may play a role, but anticholinergics were not effective.
Laxative therapy may be a viable treatment option for asthma triggered by defecation urge.