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Updated: May 13, 2026

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy
Published on: September 28, 2019
Early and late postoperative changes in the quality of life after pancreatic surgery
Orlin Belyaev1, Torsten Herzog, Ansgar M Chromik
1Department of Surgery, St. Josef Hospital, Ruhr University of Bochum, Gudrunstr. 56, 44791 Bochum, Germany. o.belyaev@klinikum-bochum.de
Purpose:
To compare health-related quality of life (QoL) before and after surgery for pancreatic disease.
Methods:
A retrospective analysis of prospectively gathered data is presented. A total of 174 patients of 230 planned for pancreatic surgery between March and December 2009 at a German high-volume center completed the Short Form-36 (SF-36) Health Survey preoperatively, 133 of them at 3 months and 83 at 24 months after surgery. Data was analysed according to diagnosis and procedure, and compared to German population norms.
Results:
QoL in the study group was worse than that of age-matched healthy population at all time points. It decreased continuously in the cancer group, decreased early and showed a trend toward recovery late in patients with benign tumors and chronic pancreatitis. Distal pancreatectomy was the best tolerated and total pancreatectomy the worst tolerated procedure. Older age and development of pancreatic insufficiency affected negatively QoL.
Conclusions:
In patients with pancreatic disease, diagnosis determined QoL preoperatively and late after surgery, while in the early postoperative period, type and extent of surgery was the leading factor. Total pancreatectomy had a profound negative effect on QoL and should be reserved for carefully selected patients only.
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