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Related Concept Videos

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
Antihypertensive Drugs: Direct Renin Inhibitors01:25

Antihypertensive Drugs: Direct Renin Inhibitors

The renin-angiotensin-aldosterone system (RAAS) is an intricate physiological pathway involving numerous enzymes and hormones, including renin, angiotensin-converting enzyme (ACE), angiotensin I and II, and aldosterone. Imbalances within this system increase the production of angiotensin II and aldosterone. Increased angiotensin II levels promote vasoconstriction and blood pressure elevation. Concurrently, higher aldosterone levels stimulate sodium and water reabsorption in the kidneys,...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
Renal Regulation of Acid-Base Balance01:29

Renal Regulation of Acid-Base Balance

Metabolic reactions in the body produce nonvolatile acids, such as sulfuric acid, which generate an acid load of approximately 1 mEq of H+ per kilogram of body weight daily. Excreting H+ in the urine is essential to balance this acid load.
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Kidney Transplant II: Surgical Procedure

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Related Experiment Video

Updated: May 13, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

[Renal denervation. Current developments].

A Saleh1

  • 1Institut für Diagnostische und Interventionelle Radiologie und Kinderradiologie, Klinikum Schwabing, Kölner Platz 1, Munich, Germany. andreas.saleh@klinikum-muenchen.de

Der Radiologe
|March 19, 2013
PubMed
Summary
This summary is machine-generated.

Renal denervation effectively lowers blood pressure in patients with resistant hypertension, reducing systolic pressure by 25-30 mmHg. This minimally invasive procedure is safe and rarely causes complications.

More Related Videos

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
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Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

Published on: June 6, 2025

Related Experiment Videos

Last Updated: May 13, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
04:37

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

Published on: June 6, 2025

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Nephrology

Context:

  • Resistant hypertension poses a significant challenge in cardiovascular disease management.
  • Catheter-based renal denervation offers a minimally invasive therapeutic option.
  • Current treatment guidelines often involve multiple antihypertensive medications.

Purpose:

  • To evaluate the efficacy and safety of renal denervation for drug-resistant hypertension.
  • To assess the impact of renal denervation on blood pressure reduction.
  • To determine the potential for medication reduction post-procedure.

Summary:

  • Renal denervation, a catheter-based endovascular procedure, aims to reduce blood pressure in drug-resistant hypertension cases.
  • In selected patients, it achieves a mean reduction of 25-30 mmHg systolic and 10-15 mmHg diastolic blood pressure.
  • Complications are rare, and current evidence does not support its use for well-controlled hypertension to discontinue medications.

Impact:

  • Provides a valuable treatment option for patients with uncontrolled hypertension.
  • Demonstrates a significant reduction in both systolic and diastolic blood pressure.
  • Highlights the safety profile of renal denervation with rare complications.