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Updated: May 13, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

New GABA amides activating GABAA-receptors

Peter Raster1, Andreas Späth, Svetlana Bultakova

  • 1Institute of Organic Chemistry, University of Regensburg, D-93040 Regensburg, Germany.

Beilstein Journal of Organic Chemistry
|March 19, 2013
PubMed
Summary

Researchers synthesized novel GABA-amides to study GABAA-receptor activation. While previously reported compounds showed no effect, new GABA-amides demonstrated moderate activation, offering potential molecular tools for receptor analysis.

Keywords:
CHO-cellsGABAGABA-amidesGABA-superagonistpatch-clamp recording

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