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Updated: May 13, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Relationship between idiopathic sudden sensorineural hearing loss and subsequent stroke
Chia-Fan Chang1, Yen-Ling Kuo, Shih-Pin Chen
1Department of Otolaryngology, Zhudong Veterans Hospital, HsinChu, Taiwan.
Idiopathic sudden sensorineural hearing loss (ISSHL) does not increase stroke risk. Patients who experienced stroke after ISSHL had pre-existing stroke risk factors, highlighting the importance of managing these factors.
Area of Science:
- Neurology
- Otolaryngology
- Epidemiology
Background:
- The relationship between idiopathic sudden sensorineural hearing loss (ISSHL) and the risk of subsequent stroke remains incompletely understood.
- Investigating this association is crucial for understanding potential shared risk factors and informing clinical management.
Purpose of the Study:
- To determine the incidence of stroke following idiopathic sudden sensorineural hearing loss (ISSHL).
- To compare the characteristics of patients who developed stroke versus those who did not after ISSHL.
Main Methods:
- A retrospective cohort study was conducted involving 349 patients diagnosed with ISSHL between 2000 and 2004.
- Patients were followed up until 2009, with stroke incidence analyzed using Cox proportional hazards regression, adjusting for key demographic and medical factors.
Main Results:
- The average annual stroke incidence rate was 0.6%, comparable to the general population.
- Patients who experienced stroke were more likely to be older and have a history of hypertension, coronary artery disease, and prior stroke.
- Prior stroke history emerged as the most significant risk factor for stroke in this cohort.
Conclusions:
- Idiopathic sudden sensorineural hearing loss (ISSHL) itself does not appear to elevate stroke risk.
- The occurrence of stroke in patients with ISSHL is primarily attributed to the presence of established stroke risk factors.
- Clinical focus should prioritize the prevention and management of modifiable stroke risk factors in patients with ISSHL.
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