Cost and effectiveness of treatment options for childhood obesity

S Hollinghurst1, L P Hunt, J Banks

  • 1Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol, UK.

Pediatric Obesity
|March 19, 2013
PubMed

Insights

Childhood obesity interventions vary in cost and effectiveness. The intensive Mandometer® approach showed significant results but at a higher price per body mass index standard deviation score (BMI SDS) reduction compared to standard care.

Area of Science:

  • Pediatric Endocrinology
  • Public Health Nutrition
  • Health Economics

Background:

  • Childhood obesity affects approximately 20% of UK children, with limited effective interventions.
  • There is a scarcity of data on the cost-effectiveness of childhood obesity interventions, hindering service commissioning.
  • Simple, multi-component interventions can be cost-effective for improving body mass index standard deviation score (BMI SDS).

Purpose of the Study:

  • To compare the costs and outcomes of three distinct childhood obesity management models.
  • To evaluate a hospital-based multidisciplinary team, a primary care nurse-led clinic, and an intensive behavioral intervention (Mandometer®).
  • To assess the cost-effectiveness of these interventions in reducing BMI SDS in children over 12 months.

Main Methods:

  • Two pilot randomized trials in England collected patient-level resource utilization data.
  • Intervention costs were primarily driven by staff time, with Mandometer® having an additional equipment cost.
  • Body mass index standard deviation score (BMI SDS) reduction at 12 months served as the primary outcome measure.

Main Results:

  • Cost per child varied: Mandometer® (£1749), primary care (£301), and hospital clinics (£263, £209).
  • Mean BMI SDS reductions were 0.40 for Mandometer®, 0.17 for primary care, and 0.15-0.14 for hospital clinics.
  • Cost per 0.1 BMI SDS reduction was £432 for Mandometer® versus £153-£173 for conventional care.

Conclusions:

  • The intensive Mandometer® intervention was effective in reducing BMI SDS but significantly more expensive than conventional care.
  • Conventional care achieved a clinically meaningful BMI SDS reduction in 26% of children.
  • Mandometer® may be a justifiable option for children unresponsive to standard lifestyle interventions.
Abstract

Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...