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Olfactory bulb control of circadian activity rhythm in mice
B Possidente1, A R Lumia, M Y McGinnis
1Biopsychology Program, Skidmore College, Saratoga Springs, NY 12866.
Brain Research
|April 16, 1990
Abstract:
Ablation of mouse olfactory bulbs lengthened the circadian period of wheel-running activity by 43 min and delayed the onset of entrained activity by 108 min. A transient increase in activity during the light phase of the 12:12 h light-dark photoperiod also occurred following surgery. These disruptions suggest that olfactory systems can modulate mammalian circadian rhythms.