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Updated: May 1, 2026

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model
Published on: June 11, 2017
The use of Ligament Advanced Reinforcement System (LARS) in limb salvage surgery: a pilot clinical study
Tao Ji1, Xiaodong Tang, Wei Guo
1Musculoskeletal Tumor Center, People's Hospital, Peking University, Beijing, China.
Abstract:
The aims of this study were to analyze the preliminary clinical outcome of limb salvage using Ligament Advanced Reinforcement System (LARS). It is hypothesized that LARS ligament is a safe and effective choice to enhance prosthetic reconstructions, providing good muscles reattachment and improving joint stability. From March 2009 to March 2010, 7 patients received megaprosthesis reconstruction following tumor resection in combination with soft tissue reconstruction using LARS. Reconstructions were four around the knee and three in proximal femur. The average MSTS 93 score was 81.0% at a mean follow-up of 27.0 months. No infection was observed. The results show that LARS appears to be an effective device for limb salvage surgery providing good muscles reattachment, improving joint stability.
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