Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Estimation of genetic parameters for pre-weaning growth traits in Dorper sheep under local Chinese conditions.

Animal bioscience·2025

Same author

Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer.

European journal of medical research·2025

Same author

Durability Investigation of Ultra-Thin Polyurethane Wearing Course for Asphalt Pavement.

Materials (Basel, Switzerland)·2024

Same author

A Meta-Analysis of Efficacy and Safety of Neoadjuvant Immunotherapy Plus Chemotherapy for Resectable Non-Small Cell Lung Cancer.

The clinical respiratory journal·2024

Same author

Estimation of Genetic Parameters of Early Growth Traits in Dumeng Sheep.

Animals : an open access journal from MDPI·2024

Same author

Expert consensus on the multidisciplinary diagnosis and treatment of multiple ground glass nodule-like lung cancer (2024 Edition).

Journal of cancer research and therapeutics·2024

Search research articles

Related Experiment Video

Updated: May 13, 2026

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

Published on: June 21, 2011

Experimental studies on few-view reconstruction for high-resolution micro-CT.

Kriti Sen Sharma¹, Xin Jin, Christian Holzner

¹Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, VA, USA.

Journal of X-Ray Science and Technology

|March 20, 2013

Summary

High-resolution micro-CT scans can be significantly faster by reducing the number of views using advanced iterative reconstruction techniques. This method maintains accuracy, enabling quicker scans, lower radiation doses, and smaller data sizes.

More Related Videos

Contrast Enhanced Vessel Imaging using MicroCT

Contrast Enhanced Vessel Imaging using MicroCT

Published on: January 27, 2011

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

Published on: October 24, 2019

Related Experiment Videos

Last Updated: May 13, 2026

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

Published on: June 21, 2011

Contrast Enhanced Vessel Imaging using MicroCT

Contrast Enhanced Vessel Imaging using MicroCT

Published on: January 27, 2011

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

Published on: October 24, 2019

Area of Science:

Medical Imaging
Computational Imaging
Materials Science

Background:

High-resolution micro-computed tomography (micro-CT) provides valuable 3D non-destructive imaging.
Current scan times are often impractically long, limiting widespread application.
Filtered back projection is the standard reconstruction method, but advanced techniques offer potential for faster scanning.

Purpose of the Study:

To investigate the feasibility of few-view reconstruction in high-resolution micro-CT.
To evaluate the accuracy of compressed-sensing based iterative reconstruction techniques.
To introduce and utilize a novel 3D micro-CT phantom for rigorous accuracy analysis.

Main Methods:

Extensive study of few-view reconstruction using compressed-sensing based iterative algorithms.
Development and application of a novel 3D micro-CT phantom for quantitative accuracy assessment.
Numerical simulations and analysis of real micro-CT data.

Main Results:

Reconstruction accuracy can be maintained even with a significant reduction in the number of views (down to 1/8th of typical acquisition).
The proposed 3D phantom enabled detailed analysis of reconstruction performance.
Performance is robust as long as measurement noise in projections is not excessively high.

Conclusions:

Advanced iterative reconstruction techniques can drastically reduce micro-CT scan times.
Few-view reconstruction is a viable strategy for high-resolution micro-CT, offering faster scanning.
Adoption of these techniques can lead to lower radiation dosage and reduced data storage requirements.