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Microfilaria in lymph node mimicking Kimura disease
Ps Jayalakshmy1, Lillykutty Pothen, V Letha
1Department of Pathology, Government Medical College, Kottayam, Kerala, India.
Tropical Parasitology
|March 20, 2013
Summary
Parasitic infections causing eosinophilia can mimic Kimura's disease in tropical regions. Careful examination of lymph nodes revealed microfilaria, enabling accurate diagnosis.
Area of Science:
- Tropical medicine
- Parasitology
- Pathology
Background:
- Parasitic infections are common in tropical and subtropical regions, often leading to eosinophilia.
- Eosinophilic infiltrates in tissues can present diagnostic challenges, sometimes resembling other conditions like Kimura's disease.
Observation:
- A case presented with intense eosinophil infiltrate in a lymph node.
- Initial tissue sections did not reveal parasitic worms, suggesting Kimura's disease.
Findings:
- Extensive sampling and microscopic examination identified microfilaria within an eosinophil abscess.
- Foreign body giant cell reaction to the microfilaria sheath confirmed the parasitic etiology.
Implications:
- This case highlights the importance of thorough examination for parasitic infections, even when initial findings are misleading.
- Accurate diagnosis of parasitic lymphadenitis is crucial for appropriate treatment and management in endemic areas.
