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Anemia among Pediatric Critical Care Survivors: Prevalence and Resolution
Quang N Ngo1, Doreen M Matsui, Ram N Singh
1Department of Pediatric Critical Care Medicine, Children's Hospital, London Health Sciences Centre, University of Western Ontario, 800 Commissioners Road East, P.O. Box 5010, London, ON, Canada N6A 5W9 ; Department of Pediatric Emergency Medicine, McMaster University, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5.
Insights
Anemia is uncommon in pediatric critical care survivors, with most cases resolving spontaneously within 4-6 months post-discharge. This study tracked hemoglobin levels in young patients after their intensive care unit stay.
Area of Science:
- Pediatric Critical Care Medicine
- Hematology
- Anemia Research
Background:
- Anemia is a potential complication for pediatric critical care survivors.
- Understanding the incidence and resolution of anemia is crucial for long-term patient outcomes.
Purpose of the Study:
- To investigate the occurrence of anemia in children discharged from the pediatric critical care unit (PCCU).
- To assess the spontaneous resolution of anemia within six months after discharge.
Main Methods:
- A prospective observational study design was employed.
- Patients aged 28 days to 18 years, treated in a tertiary care PCCU for over 24 hours, were included.
- Hemoglobin levels were monitored in-hospital and during a 4-6 month post-discharge follow-up for anemic patients.
Main Results:
- Out of 392 eligible patients, 94 (24%) were anemic at discharge.
- Anemic patients were older and had higher PeLOD and PRISM scores.
- Hemoglobin normalized before hospital discharge in 32% of patients; all followed-up patients showed normalization without intervention.
Conclusions:
- Anemia is not highly prevalent among pediatric critical care survivors at discharge.
- The majority of anemia cases in this population resolve spontaneously within 4-6 months without specific medical treatment.
Abstract:
To determine the incidence of anemia among pediatric critical care survivors and to determine whether it resolves within 6 months of discharge. Design. A prospective observational study. Patients with anemia upon discharge from the pediatric critical care unit (PCCU) underwent in hospital and post hospital discharge followup (4-6 months) for hemoglobin (Hb) levels. Setting. A medical-surgical PCCU in a tertiary care center. Patients. Patients aged 28 days to 18 years who were treated in the PCCU for over 24 hours. Measurements and Main Results. 94 (24%) out of 392 eligible patients were anemic at time of discharge. Patients with anemia were older, median 8.0 yrs [(IQR 1.0-14.4) versus 3.2 yrs (IQR 0.65-9.9) (P < 0.001)], and had higher PeLOD [median 11 (IQR 10-12) versus 1.5 (1-4) (P < 0.001)], and PRISM [median 5 (IQR 2-11) versus 3 (IQR 0-6) (P < 0.001)] scores. The Hb level normalized in 32% of patients before discharge from hospital. Of the 28 patients who completed followup, all had normalization of their Hb in the absence of medical intervention. Conclusions. Anemia is not common among patients discharged from the PCCU and recovers spontaneously within 4-6 months.
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