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Deltamethrin induced toxicity and ameliorative effect of alpha-tocopherol in broilers
Naresh Chandra1, N K Jain, Shobha Sondhia
1Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Madhya Pradesh Pashu Chikitsa Vigyan Vishwavidyalaya, Jabalpur, M.P., India. drncvet@gmail.com
Bulletin of Environmental Contamination and Toxicology
|March 21, 2013
Summary
Deltamethrin (DM) insecticide exposure reduced broiler bird growth, with higher residues in liver. Alpha-tocopherol partially counteracted these negative effects, indicating a potential protective role.
Area of Science:
- Toxicology
- Animal Science
- Agricultural Science
Background:
- Deltamethrin (DM) is a widely used insecticide for crop protection.
- Exposure to DM poses risks to non-target organisms, including birds, potentially impacting growth.
- Understanding DM toxicity and potential mitigation strategies is crucial for animal health and food safety.
Purpose of the Study:
- To investigate the toxic effects of Deltamethrin (DM) on broiler birds.
- To evaluate the ameliorative effects of alpha-tocopherol against DM-induced toxicity.
- To quantify DM residue levels in different tissues of broiler chickens.
Main Methods:
- Broiler birds were administered Deltamethrin (DM) or DM with alpha-tocopherol daily for 42 days.
- Body weight was monitored weekly.
- DM residues were quantified in liver, breast, and leg muscles post-exposure.
Main Results:
- DM exposure led to a dose-dependent decrease in body weight in broiler birds.
- Alpha-tocopherol supplementation partially restored body weight in DM-exposed birds.
- Higher DM residues were detected in the liver compared to breast and leg muscles.
Conclusions:
- Deltamethrin (DM) exposure negatively impacts broiler growth performance.
- Alpha-tocopherol demonstrates partial protective effects against DM toxicity in broiler chickens.
- Liver accumulates higher levels of DM residues, suggesting it as a primary target organ.
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