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Updated: May 13, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

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Published on: July 11, 2025

Complications and side effects: a problem in general practice?

M Conradi1, K Groenier, J Hutten

  • 1Department af General Practice, University af Groningen, The Netherlands.

The International Journal of Risk & Safety in Medicine
|March 21, 2013
PubMed
Summary
This summary is machine-generated.

Iatrogenic illnesses, including medication side effects and treatment complications, impact 2% of general practice contacts. Patients experiencing these issues face double the risk of serious harm or life-threatening conditions, highlighting a significant problem in primary care.

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Last Updated: May 13, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Area of Science:

  • General Practice
  • Patient Safety
  • Public Health

Background:

  • Iatrogenic illnesses represent a significant concern in healthcare delivery.
  • Understanding the prevalence and severity of iatrogenic harm in primary care is crucial for improving patient outcomes.
  • Previous research has not fully elucidated the extent of these issues within the general practice setting.

Purpose of the Study:

  • To investigate the nature and extent of iatrogenic illnesses in Dutch general practice.
  • To quantify the frequency of medication side effects and complications of medical treatment as diagnoses or considerations by general practitioners (GPs).
  • To assess the severity of iatrogenic harm experienced by patients in primary care.

Main Methods:

  • Secondary analysis of data from the 'Dutch National Survey of Morbidity and Intervention in General Practice'.
  • Inclusion of 386,000 patient contacts with 161 GPs, coded using the International Classification of Primary Care (ICPC).
  • Focus on diagnoses related to 'side effects of medication' and 'complications of medical treatment'.

Main Results:

  • Approximately 2% of all patient contacts in general practice involved diagnoses or considerations of medication side effects or treatment complications.
  • Patients experiencing iatrogenic harm were, on average, twice as likely to suffer serious invalidating conditions or face life-threatening situations.
  • These two categories of iatrogenic harm represent a substantial issue within general practice.

Conclusions:

  • Iatrogenic illnesses are an important and prevalent problem in general practice.
  • The identified rate of 2% highlights a need for increased vigilance and preventative strategies.
  • The heightened risk of severe outcomes underscores the critical impact of iatrogenic harm on patient well-being and safety.