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Updated: May 13, 2026

Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules
Published on: May 23, 2015
A comparative needle study: EUS-FNA procedures using the HD ProCore(™) and EchoTip(®) 22-gauge needle types
Benjamin L Witt1, Douglas G Adler, Kristen Hilden
1Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah.
The beveled endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) needle showed similar diagnostic results to the standard needle. This beveled needle may reduce the number of passes needed for adequate samples in EUS-FNA procedures.
Area of Science:
- Gastroenterology
- Endoscopic Ultrasound
- Cytopathology
Background:
- Needle selection for endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) impacts sample quality.
- The HD ProCore™ beveled needle offers core biopsy capabilities alongside aspiration.
Purpose of the Study:
- To compare the diagnostic yield and efficiency of a 22-gauge beveled EUS-FNA needle against a standard 22-gauge needle.
- To evaluate cytological parameters, cell block adequacy, and procedural efficiency.
Main Methods:
- A comparative study of 18 patients using the HD ProCore™ beveled needle versus 18 patients using a standard 22-gauge needle for EUS-FNA.
- Assessment of cytological smears and cell blocks for cellularity and diagnostic material.
- Review of records for sample adequacy, number of passes, and procedure duration.
Main Results:
- Both needles yielded similar results in cytology parameters, cell block adequacy, and diagnostic accuracy.
- The beveled needle group required fewer passes (2.11) to achieve adequacy compared to the standard needle group (2.94, P=0.03).
- No significant difference in procedure duration or reported complications was observed.
Conclusions:
- The beveled EUS-FNA needle is a diagnostically comparable alternative to standard needles.
- A trend towards improved per-pass adequacy suggests the beveled needle may enhance efficiency.
- Further studies are warranted to confirm the improved per-pass adequacy of the beveled needle.
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