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Propofol compared with combination propofol or midazolam/fentanyl for endoscopy in a community setting
John E Poulos1, Peter T Kalogerinis, Jeffrey N Caudle
1Fayetteville Gastroenterology Associates, North Carolina, USA. poulosj@pol.net
AANA Journal
|March 22, 2013
Summary
Propofol sedation significantly reduced procedure and recovery times for both colonoscopy and esophagogastroduodenoscopy. Patients receiving propofol reported less discomfort and better satisfaction compared to other sedation methods.
Area of Science:
- Gastroenterology
- Anesthesiology
- Clinical Pharmacology
Background:
- Sedation is crucial for patient comfort and procedural success during endoscopic procedures.
- Traditional sedation regimens (e.g., midazolam/fentanyl) may be associated with longer procedural and recovery times.
- Optimizing sedation protocols can improve patient experience and endoscopy unit efficiency.
Purpose of the Study:
- To compare the procedural efficiency and patient satisfaction of propofol versus midazolam/fentanyl/propofol (MFP) or midazolam/fentanyl sedation.
- To evaluate the impact of different sedation agents on procedure duration, recovery time, and patient-reported outcomes.
Main Methods:
- Retrospective cohort study design.
- Inclusion of patients undergoing esophagogastroduodenoscopy or colonoscopy.
- Data collection via questionnaires assessing procedural times and patient satisfaction.
Main Results:
- Propofol significantly shortened induction-to-procedure start time, procedure duration, and recovery time for colonoscopy compared to MFP and midazolam/fentanyl.
- For esophagogastroduodenoscopy, propofol also resulted in significantly shorter recovery times.
- Patients receiving propofol reported less discomfort, fewer sedation adjustments, and less recall of the procedure.
Conclusions:
- Propofol is a more efficient sedation agent for endoscopic procedures, leading to reduced patient time in the endoscopy unit.
- Propofol administration enhances patient satisfaction through quicker recovery, discharge, and improved comfort.
- These findings support the use of propofol for optimizing sedation in gastrointestinal endoscopy.
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