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Related Experiment Video

Updated: May 13, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Super giant squamous cell carcinomas.

Luís Ricardo Martinhão Souto¹, Rafael Denadai Pigozzi Silva

¹School of Medical Sciences, Universidade de Marília (UNIMAR), São Paulo, Brazil. Irmsouto@yahoo.com.br

|March 22, 2013

Summary

Super giant squamous cell carcinomas (SCCs), rare and aggressive tumors, pose significant treatment challenges. Surgical excision proved effective in two cases, with no recurrence or metastasis observed after 24 months.

Area of Science:

Dermatology
Surgical Oncology
Oncology

Background:

Squamous cell carcinomas (SCCs) exceeding 2 cm present increased risks of disfigurement, recurrence, and metastasis.
Giant SCCs are uncommon and can infiltrate critical aesthetic and functional structures, complicating treatment and impacting patient quality of life.

Observation:

This report details two rare cases of super giant SCCs with prolonged development.
Both cases involved SCCs that infiltrated nearby structures, necessitating extensive surgical intervention.

Findings:

Successful treatment was achieved through surgical excision in both super giant SCC cases.
Post-treatment follow-up for 24 months revealed no evidence of local recurrence or metastasis in either patient.

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Published on: August 9, 2024

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

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Published on: December 23, 2022

Implications:

Surgical excision can be a viable and effective treatment for super giant SCCs.
These findings suggest that radical surgical management can lead to favorable long-term outcomes, even for extensive tumors.