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Updated: May 13, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Isolated diffuse episcleral neurofibroma
Mohamed Naeem Mohyudin1, Misha Darrad, Aidan Murray
1Department of Ophthalmology, Birmingham Midlands Eye Centre, Birmingham, United Kingdom. mnmohyudin@doctors.org.uk
Aims:
To report a rare case of isolated diffuse episcleral neurofibroma and to discuss possible differential diagnoses.
Case Report:
A 37 year old Caucasian female was found to have an epibulbar tumour arising from the superior aspect of her left eye. Clinical examination revealed a 12 mm × 8 mm "salmon pink" coloured lesion.
Results:
A biopsy was performed and histopathologic examination and subsequent systemic evaluation showed it to be a rare case of isolated diffuse episcleral neurofibroma.
Conclusion:
There are many differential diagnoses for an epibulbar lesion and neurofibroma should be added to these. Even though a small risk of malignant transformation exists, we recommend a conservative approach for slow growing lesions.

