Related Experiment Video
Updated: May 13, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
Published on: October 13, 2011
Topological features in stretching of proteins
Marek Cieplak1, Mateusz Sikora
1Laboratory of Biological Physics, Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/48, Warsaw, Poland. mc@ifpan.edu.pl
Abstract:
In the present article, we highlight the diversity of mechanical clamps, some of them topological in nature, that have been found by making surveys of mechanostability of approximately 18000 proteins within structure-based models. The existence of superstable proteins (with the characteristic unfolding force in the region of 1000 pN) is predicted.
Related Concept Videos
Protein Folding
Protein Folding
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
Protein Folding
Protein and Protein Structure
A protein's shape is critical to its function. For example, an enzyme can...
Protein Organization
Protein Organization
The primary structure of a protein is its amino acid sequence.

