Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification and management of different types of bacillary layer detachment in eyes with rhegmatogenous retinal detachment.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

The Side-Steamroll: a Modified Steamroller Maneuver to Control Fluid Displacement After Pneumatic Retinopexy.

Retinal cases & brief reports·2026
Same author

Engineering Komagataella phaffii for secreted and surface-displayed production of SARS-CoV-2 receptor-binding domain and its immunogenicity evaluation.

Microbial cell factories·2026
Same author

Marginal Outer Retinal Ridge Following Rhegmatogenous Retinal Detachment Repair: A Novel Biomarker of Retinal Displacement.

Ophthalmology. Retina·2026
Same author

5' leader defects drive persistent HIV-1 viremia on long-term ART.

Nature communications·2026
Same author

Associations of age-related macular degeneration and statin use: a cross-sectional analysis.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same journal

Ocular toxoplasmosis in Latin American and European patients: clinical characteristics, visual outcomes, and recurrence patterns.

Journal of ophthalmic inflammation and infection·2026
Same journal

Severe corneal melting with necrotic sloughing in Acanthamoeba keratitis mimicking corneal endotheliitis.

Journal of ophthalmic inflammation and infection·2026
Same journal

Delayed-onset cytomegalovirus retinitis after 0.2 µg/day fluocinolone acetonide implantation: a case series.

Journal of ophthalmic inflammation and infection·2026
Same journal

Evaluation of corneal intrastromal voriconazole injection as an adjuvant approach in recalcitrant fungal keratitis.

Journal of ophthalmic inflammation and infection·2026
Same journal

Occlusive retinal vasculopathy on ultrawide-field fluorescein angiography in intraocular cytomegalovirus infection: a case series.

Journal of ophthalmic inflammation and infection·2026
Same journal

Nocardia brasiliensis endophthalmitis initially misdiagnosed as uveitis: a case report.

Journal of ophthalmic inflammation and infection·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Post-traumatic vancomycin-resistant enterococcal endophthalmitis.

Roxane J Hillier1, Parnian Arjmand, Gabriel Rebick

  • 1Ophthalmology Department, St Michael's Hospital, 801-61 Queen Street East, Toronto, ON, M5C 2T2, Canada. roxanehillier@gmail.com.

Journal of Ophthalmic Inflammation and Infection
|March 22, 2013
PubMed
Summary
This summary is machine-generated.

A rare case of severe eye infection caused by vancomycin-resistant Enterococcus gallinarum after trauma was successfully treated. This highlights the need for alternative antibiotic strategies against multidrug-resistant organisms in ophthalmology.

More Related Videos

Intracameral Injection in Rats with Low Risk of Adverse Effects
06:19

Intracameral Injection in Rats with Low Risk of Adverse Effects

Published on: May 31, 2024

Related Experiment Videos

Last Updated: May 13, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Intracameral Injection in Rats with Low Risk of Adverse Effects
06:19

Intracameral Injection in Rats with Low Risk of Adverse Effects

Published on: May 31, 2024

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Severe ocular infections pose a significant threat, exacerbated by rising antibiotic resistance.
  • Multidrug-resistant organisms (MDROs) present complex challenges in treating eye infections.

Purpose of the Study:

  • To report the first case of endophthalmitis caused by vancomycin-resistant Enterococcus gallinarum following ocular trauma.
  • To discuss effective treatment strategies for this unique and challenging clinical presentation.

Main Methods:

  • A patient with endophthalmitis post-ocular trauma was diagnosed with Enterococcus gallinarum infection.
  • Antimicrobial susceptibility testing was performed to guide treatment.
  • The patient received a combination therapy of intravitreal and intravenous ampicillin, along with intravitreal amikacin.

Main Results:

  • The causative organism, Enterococcus gallinarum, exhibited intrinsic resistance to ceftazidime and vancomycin.
  • The patient showed a favorable response to the prescribed combination antibiotic regimen.
  • Successful management of a rare MDRO-causing endophthalmitis was achieved.

Conclusions:

  • Vancomycin-resistant Enterococcus gallinarum can cause severe endophthalmitis after ocular trauma.
  • Alternative antibiotic regimens, including ampicillin and amikacin, are effective against this resistant pathogen.
  • Ophthalmologists must consider novel therapeutic approaches when managing MDROs in ocular infections.