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Genome Sequence of Staphylococcus pseudintermedius Strain E140, an ST71 European-Associated Methicillin-Resistant

Arshnee Moodley1, Matthew C Riley, Stephen A Kania

  • 1Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Copenhagen, Denmark.

Genome Announcements
|March 22, 2013
PubMed

Insights

We sequenced the first methicillin-resistant Staphylococcus pseudintermedius (MRSP) genome from a Danish canine infection. This strain is the main type causing MRSP infections in dogs across Europe.

Area of Science:

  • Veterinary Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is a significant pathogen in canine infections.
  • Understanding the genetic makeup of dominant MRSP strains is crucial for controlling their spread.

Purpose of the Study:

  • To present the complete genome sequence of the MRSP strain E140.
  • To characterize the genetic features of a prevalent MRSP lineage in Europe.

Main Methods:

  • Whole-genome sequencing of MRSP strain E140.
  • Bioinformatic analysis of the obtained genome sequence.

Main Results:

  • The genome sequence of MRSP strain E140 was successfully obtained.
  • Strain E140 was isolated from a canine bite wound infection in Denmark.
  • This strain belongs to the dominant clonal lineage responsible for canine MRSP infections in Europe.

Conclusions:

  • The genome sequence provides a valuable resource for studying MRSP epidemiology and evolution.
  • This finding highlights the importance of surveillance for dominant MRSP lineages in companion animals.

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