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Identification of a new HLA-C allele, HLA-C*08:76 in a Caucasian individual

E A Gonzalez1, A Mensa, P Villarroel

  • 1Servei d'Immunologia, Hospital Clinic, Barcelona, Spain.

Tissue Antigens
|March 23, 2013
PubMed

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Genome-wide Association Studies-GWAS01:11

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...