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Updated: May 13, 2026

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children
Published on: April 29, 2013
Gender differences in cardiac autonomic modulation during medical internship
Yu-Hsuan Lin1, Ching-Yen Chen, Sheng-Hsuan Lin
1Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.
Medical interns face high stress, potentially impacting health. Male interns showed decreased heart rate variability and increased depressive symptoms over time, unlike females.
Area of Science:
- Cardiology
- Psychiatry
- Occupational Health
Background:
- Medical internships involve high stress and long hours, increasing risks for depression and cardiovascular disease.
- Previous research has not detailed gender-specific cardiovascular risks during medical internships.
Purpose of the Study:
- To investigate gender differences in cardiovascular risk and depressive symptoms among medical interns.
- To analyze changes in heart rate variability (HRV) and depression scores throughout the internship period.
Main Methods:
- Longitudinal study involving 38 medical interns (29 males).
- Repeated assessments of depressive symptoms using the Hospital Anxiety and Depression Scale.
- 5-minute spectral analysis of heart rate variability (HRV) conducted at 3-month intervals.
Main Results:
- Male interns exhibited decreased heart rate variance at 6, 9, and 12 months.
- Reduced cardiac parasympathetic modulation (indicated by lower high-frequency HRV) was observed in males at 9 and 12 months.
- Male interns reported increased depressive symptoms at 12 months; no significant changes were found in female interns.
Conclusions:
- Male medical interns may experience significant cardiovascular autonomic regulation changes and increased depression during their internship.
- Female interns did not show similar detrimental changes in HRV or depressive symptoms.
- Findings highlight potential gender-specific vulnerabilities to internship stress impacting intern health.
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